Intraventricular glioblastoma

Glioblastoma (World Health Organization [WHO] grade IV), one of the most malignant central nervous system (CNS) cancers in children and adults, is characterized by architectural diversity and cellular heterogeneity [1]; it is a common primary brain tumor, which constitutes about 25% of all intracranial tumors in adults [2,3]. Being known as the most malignant primary brain tumor, GBM may arise theoretically anywhere within the central nervous system (CNS) [2,3]. However Glial tumors mostly present in cerebral hemispheres (86%), only a very small percent of them (2.2%) present in the ventricles [4]. We present a case of an Intraventricular Glioblastoma, which has been managed with stereotactic biopsy and adjuvant chemoradiotherapy. We discuss clinical, radiological, therapeutic aspects of this rare pathology, with a literature review.